{"id":2014,"date":"2025-01-04T16:01:43","date_gmt":"2025-01-04T12:31:43","guid":{"rendered":"https:\/\/www.rtzco.com\/?p=2014"},"modified":"2025-01-05T08:54:07","modified_gmt":"2025-01-05T05:24:07","slug":"%d9%86%d9%82%d8%b4-%d8%b3%d9%84%d9%86%db%8c%d9%88%d9%85-%d9%88-%d9%88%db%8c%d8%aa%d8%a7%d9%85%db%8c%d9%86-%d9%87%d8%a7%db%8c-e-%d9%88-b9-%d8%af%d8%b1-%da%a9%d8%a7%d9%87%d8%b4-%d9%88%d8%b1%d9%85-%d9%be","status":"publish","type":"post","link":"https:\/\/www.rtzco.com\/de\/2025\/01\/04\/%d9%86%d9%82%d8%b4-%d8%b3%d9%84%d9%86%db%8c%d9%88%d9%85-%d9%88-%d9%88%db%8c%d8%aa%d8%a7%d9%85%db%8c%d9%86-%d9%87%d8%a7%db%8c-e-%d9%88-b9-%d8%af%d8%b1-%da%a9%d8%a7%d9%87%d8%b4-%d9%88%d8%b1%d9%85-%d9%be\/","title":{"rendered":"Die Rolle von Selen und den Vitaminen E und B9 bei der Reduzierung der Rindermastitis in der Zeit nach der Geburt"},"content":{"rendered":"
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Mastitis (Entz\u00fcndung der Milchdr\u00fcse) tritt bei Milchk\u00fchen h\u00e4ufig in der Zeit nach der Geburt (\u00dcbergangszeit) auf, wenn Milchk\u00fche physiologische und hormonelle Ver\u00e4nderungen und eine schwere negative Energiebilanz erfahren, gefolgt von oxidativem Stress. Um eine erfolgreiche Laktation aufrechtzuerhalten und eine negative Energiebilanz (NEB) zu bek\u00e4mpfen, kommt es zu einer Hypermobilit\u00e4t des Fetts, die zu einer \u00fcberm\u00e4\u00dfigen Produktion reaktiver Sauerstoffspezies (ROS) f\u00fchrt. Hyperlipid\u00e4mie erh\u00f6ht auch die Konzentrationen von nicht veresterten Fetts\u00e4uren (NEFA) und \u03b2-Hydroxybutters\u00e4ure (BHB) w\u00e4hrend der Zeit nach der Geburt. Dar\u00fcber hinaus f\u00fchrt die \u00fcberm\u00e4\u00dfige Nutzung von Sauerstoff durch die Zellatmung in der Milchdr\u00fcse zu einer abnormalen Produktion von oxidativem Stress (OS), der die Immunit\u00e4t und entz\u00fcndungshemmende Wirkung von Milchk\u00fchen w\u00e4hrend der Geburt beeintr\u00e4chtigt und ihre Anf\u00e4lligkeit f\u00fcr Mastitis erh\u00f6ht Um oxidativen Stress und daraus resultierende Mastitis zu reduzieren, werden Milchk\u00fchen Antioxidantien aus einer externen Quelle zugef\u00fchrt. Es wurden umfangreiche Studien zur Erg\u00e4nzung von Selen (Se) und den Vitaminen E und B9 durchgef\u00fchrt, um Mastitis w\u00e4hrend der \u00dcbergangszeit bei Milchk\u00fchen zu reduzieren.<\/p>

Eine aktuelle Studie zeigte, dass oxidativer Stress die Hauptursache f\u00fcr Perinatalerkrankungen bei Milchk\u00fchen ist. In \u00e4hnlicher Weise wurde in einer anderen Studie berichtet, dass eine \u00dcberproduktion von ROS zu oxidativem Stress f\u00fchrt, der die Immunit\u00e4t und entz\u00fcndungshemmenden Funktionen bei Milchk\u00fchen w\u00e4hrend der \u00dcbergangszeit beeintr\u00e4chtigt. Aufgrund der Unterdr\u00fcckung des Immunsystems nimmt die Empfindlichkeit von Milchk\u00fchen gegen\u00fcber Mastitis im Perinatalstadium zu. Wie bereits erw\u00e4hnt, sind eine negative Energiebilanz und Stoffwechselst\u00f6rungen Schl\u00fcsselfaktoren f\u00fcr oxidativen Stress in der Zeit nach der Geburt bei Milchk\u00fchen. Daher kommen wir aus der vorherigen Diskussion zu dem Schluss, dass das Ern\u00e4hrungsmanagement einer der effizientesten Ans\u00e4tze sein kann, um die antioxidative Kapazit\u00e4t von Tieren zu erh\u00f6hen und oxidativen Stress zu verhindern, der Milchk\u00fche w\u00e4hrend der \u00dcbergangszeit anf\u00e4llig f\u00fcr Mastitis macht.<\/p>

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Eine negative Energiebilanz f\u00fchrt bei Milchk\u00fchen w\u00e4hrend der Geburt zu einer Hypermobilit\u00e4t des Fetts, was zu erh\u00f6hten NEFA- und ROS-Werten und damit zu oxidativem Stress f\u00fchrt. Oxidativer Stress f\u00fchrt au\u00dferdem zu einer abnormalen Immunregulation und Entz\u00fcndung, wodurch Milchk\u00fche anf\u00e4lliger f\u00fcr Mastitis werden. Eine abnormale Immunregulation und Entz\u00fcndungen f\u00fchren auch zu Lipidhypermobilit\u00e4t und oxidativem Stress, was die TNF-\u03b1-\u00dcberproduktion aktiviert.<\/p>

Insgesamt kommen wir zu dem Schluss, dass die Zeit nach der Geburt bei Milchk\u00fchen kritisch ist und sie f\u00fcr Mastitis pr\u00e4disponiert. Zu den Schl\u00fcsselfaktoren, die dazu f\u00fchren, dass Milchk\u00fche w\u00e4hrend der \u00dcbergangszeit anf\u00e4llig f\u00fcr Mastitis sind, geh\u00f6ren eine negative Energiebilanz, gefolgt von einer Hypermobilit\u00e4t von Fett, oxidativem Stress und daraus resultierender abnormaler Immunregulation und Entz\u00fcndung. W\u00e4hrend der Perinatalperiode leiden Milchk\u00fche unter einem schweren Mangel an einigen wichtigen N\u00e4hrstoffen (Vitamin E, Fols\u00e4ure und Selen), der sie f\u00fcr Mastitis pr\u00e4disponiert. Vitamin- (E und Fols\u00e4ure) und Se-Erg\u00e4nzungen wirken sich positiv auf die Immunregulation aus und reduzieren den oxidativen und entz\u00fcndlichen Status bei Milchk\u00fchen w\u00e4hrend der postpartalen Phase. Daher wird vorgeschlagen, dass Nahrungserg\u00e4nzungsmittel mit Fols\u00e4ure, Selen und Vitamin E w\u00e4hrend der \u00dcbergangszeit als therapeutische Erg\u00e4nzung zur Reduzierung von Mastitis bei Milchk\u00fchen in Betracht gezogen werden k\u00f6nnen.<\/p>

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[Quelle: https:\/\/www.mdpi.com\/2076-3921\/11\/4\/657<\/a><\/p><\/div>","protected":false},"excerpt":{"rendered":"

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