There are several additives that can be used to prevent ketosis in transitioning dairy cows. Some of the commonly used options are:

Propylene Glycol: Propylene glycol is a common additive to prevent ketosis in dairy cows. It is a source of glucose precursors that can help meet the energy needs of cows during the transition period. Propylene glycol is commonly administered orally and is readily absorbed and converted to glucose in the liver.

Glycerol: Glycerol is another additive that can be used to prevent ketosis. Similar to propylene glycol, it is a source of glucose precursors. Glycerol can be incorporated into the diet or used orally to provide additional energy and support glucose production in cows during the transition period.


Calcium propionate: Calcium propionate is a good source for prevention and treatment of hypocalcemia and ketosis for dairy cows in early lactation.

Niacin: Niacin or vitamin B3 has beneficial effects in preventing ketosis. It plays a role in energy metabolism and can help improve glucose utilization in cattle. Niacin can be added to the diet or given as a supplement to support metabolic functions during the transition period.


Choline: Choline is an essential nutrient involved in lipid metabolism and liver function. It can help improve liver health and prevent the accumulation of fat in the liver that is associated with ketosis. Including choline in the diet or providing it as a supplement can help support liver function and reduce the risk of ketosis.

Yeast cultures: Yeast cultures such as Saccharomyces cerevisiae have been shown to improve rumen fermentation and improve fiber digestion. By promoting efficient rumen function, yeast culture can help maintain a stable energy balance and reduce the risk of ketosis. Yeast culture can be added to the diet as a feed additive.
It is important to note that the effectiveness of additives may vary depending on specific management practices, cow health status, and overall feeding program. In addition, it is important to consult with a veterinarian or a qualified nutritionist to determine the appropriate additives and their inclusion levels based on the specific needs of your herd. They can assess the nutritional needs of the herd and develop a comprehensive plan to prevent ketosis during the transition period.